A new drug Application has been submitted by Genzyme and Pharmaceuticals Inc., for mipomersen sodium (named Kynamaro), for the treatment of patients with homozygous familial hypercholesterolemia (HoFH). HoFH is caused by a rare genetic disorder and characterized by high cholesterol levels, specifically high LDL (bad cholesterol) levels. As this disorder is present from birth, like any other genetic disorder, atherosclerotic changes may begin early in life, resulting in aggressive heart disease beginning in childhood. The drugs and therapies used to treat that lowers LDL levels are not effective and the patients face significant risk of cardiovascular events.

Currently available therapies for HoFH work on clearing LDL and include LDL-aphereis (similar to dialysis) or liver transplant. Kynamaro targets the production of LDL and other lipoproteins to lower the LDL levels in blood. Kynamaro is another new addition to the new generation of personalized drugs that target specific conditions. Kynamaro may be used in treating patients with severe heterozygous familial hypercholesterolemia (Severe HeFH) for lowering their LDL levels in the blood. Genzyme’s application to FDA is supported by the largest clinical trial conducted to date in the HoFH patient population.

According to senior pharmacist at Big Mountain Drugs, Canada, a large percentage of their customers are purchasing a wide range of cholesterol drugs. Cholesterol lowering drugs have been widely used for lowering the risk of heart disease among high risk patients like those with hypertension. According to the BMD spokesperson, widely used cholesterol lowering drugs in their portfolio are Lipitor (Atorvastatin), Tricor (Fenofibrate), Zocor (Simvastatin), Mevacor (Lovastatin) and Lescol (Fluvastatin).

The MBD spokesperson further added, “We supply best quality drugs at affordable prices. Our wide range of products, include brand name drugs, generic drugs and over the counter medications. We have a large number of cholesterol lowering drugs, both brand-name and generic. Our customers enjoy lower prices, attractive discounts on already low prices and the delivery to the doorstep service. Our team of Customer service agents can speak more than twelve languages and they are ready to answer the customer queries regarding the drugs.” BMD’s 5% reward scheme has been designed to reward the customers who regularly buy drugs from BMD, giving a 5% off on next bill when you make a purchase currently.

Big Mountain Drugs is a licensed pharmacy registered in British Columbia. It serves the customers around the world through its website BigMountainDrugs.com, in addition to operating physical brick and mortar pharmacies in British Columbia. It has been licensed by the College of Pharmacists of British Columbia, regulating authority for pharmacies in British Columbia. BMD is a verified member of prestigious Canadian International Pharmacy Association (CIPA). CIPA is the only organization that certifies Canadian pharmacies supplying to international customers. CIPA certification guarantees that a pharmacy is registered and licensed and follows legal, ethical and professional standards of the profession of pharmacy. BMD has been verified by PharmacyChecker.com, an independent company verifying the international pharmacies.

Author:
Big Mountain Drugs provides a wide portfolio of branded and generic prescription as well as OTC Drugs at affordable prices via its licensed Canada online pharmacy. Customers can now Buy Crestor or Generic Crestor and other Canada prescription drugs from BMD and have it delivered worldwide to their doorstep. Big Mountain Drugs is a CIPA approved pharmacy operating from British Colombia, Canada.

For more information on Big Mountain Drugs.Com:
Name : Ms. Estella Wong
Tel : 1.778.218.2670
Web : http://www.bigmountaindrugs.com/
BigMountainDrugs.com
8322 130th Street, Surrey,
British Columbia, Canada, V3W 8J9